Anthracycline metabolites from Streptomyces violaceus A262. III. New anthracycline obelmycins produced by a variant strain SE2-2385.

نویسندگان

  • O Johdo
  • Y Watanabe
  • T Ishikura
  • A Yoshimoto
  • H Naganawa
  • T Sawa
  • T Takeuchi
چکیده

New anthracycline antibiotics, designated as obelmycins A, D, E, F and G, were isolated from the culture broth of a variant strain of beta-rhodomycin-producing Streptomyces violaceus A262, identified as beta-isorhodomycinone glycosides and gamma-isorhodomycinone glycosides and assayed for their in vitro cytotoxicities against murine leukemic L1210 cell culture and the antimicrobial activities in comparison with some known anthracyclines.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 44 10  شماره 

صفحات  -

تاریخ انتشار 1991